α β-γ δ-unsaturated-γ-lactone 309887

Contaminantdb 4 Hydroxy 2 Butenoic Acid Gamma Lactone

Aqueous HF promotes the translactonization of silyloxy βlactones into βhydroxy or α,βunsaturated γ and δlactones The reaction is studied from a An organocatalytic Michaelcyclization cascade of aldehydes with 4oxaα,βunsaturated carboxylic acids has been developed, giving functionalized γlactols with high yields and enantioselectivities The products could be easily transformed into complex trisubstituted γlactones and γlactams

α β-γ δ-unsaturated-γ-lactone

α β-γ δ-unsaturated-γ-lactone-The synthesis of a series of αmethyleneγbutyrolactones (compounds 4a, 4b, 6–12, 16, 17) and α,βunsaturatedδlactones (compounds 19−23, 25,A preparatively useful onestep transformation of γ,γdisubstituted αformylγlactones into trisubstituted γ,δunsaturated aldehydes is described, by means of catalytic amounts of either

Biosynthetic Investigation Of G Lactones In Sextonia Rubra Wood Using In Situ Tof Sims Ms Ms Imaging To Localize And Characterize Biosynthetic Intermediates Scientific Reports

Two novel and convenient routes to obtain enantiomerically enriched transβarylδhydroxyγlactones 5a–d with potential antifeedant and anticancer activity were developed In the first method starting from corresponding enantiomers of γ,δunsaturated esters 4a–d derived from enzymatically resolved allyl alcohols 1a–d, both enantiomers of hydroxylactones 5a–d were The Rucatalyzed cyclocarbonylation of α or βallenic sulfonamides in the presence of Ru3(CO)12 (1 mol %) and Et3N (15 equiv) under CO atmosphere ( atm) in dioxane at 100 °C for 9 h gave heterocyclic γ and δunsaturated lactams in good yieldsAccordingly, the α,β,γ,δunsaturated lactone patulin (PAT), a mycotoxin detected in fruits and products derived thereof, is known to induce gene, chromosome, and genome mutations in vitro, its mutagenicity correlating inversely with intracellular GSH levels Thus, the reactivity of PAT against DNA bases and nucleosides in the absence and presence of GSH and glutathione Stransferases

Diversely Substituted SugarLinked α,βUnsaturated γLactones from SugarDerived Baylis−Hillman Adducts via a RCM Journal of Combinatorial Chemistry 07 , 9 (1) , 6269 During an ongoing exploration of potential antiinflammatory agents from medicinal plants, eight new arylalkenyl α,βunsaturated δlactones, cryptoconcatones A–H (1–8), and two unusual arylalkenyl α,βunsaturated γlactones, cryptoconcatones I and J (9 and 10), were identified from the leaves and twigs of Cryptocarya concinna The structures of these Here we report an efficient asymmetric 42 cycloaddition of β,γunsaturated αketoesters with cyclobutenones The corresponding products were obtained in good yields (up to 92%) with excellent enantioselectivities (up to 98% ee) and diastereoselectivities (up to >19/1 dr) Moreover, based on the control experiments and previous reports, a possible catalytic cycle was

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An enantioselective synthesis of α,βunsaturated γ and δlactams was proposed based on a simple strategy using the initial preparation of cis vinylogous aminoesters by the Horner reaction followed by a mild intramolecular cyclisation Graphic Download Download fullsize image;The photochemical cycloaddition reactions of five and sixmembered α,βunsaturated lactone derivatives with unsaturated substrates (ethylene, acetylene, 1,1dimethoxyethylene etc) have been studied The parent α,βunsaturated lactone (γcrotonolactone) and the β,γ, or δalkyl substituted derivatives add to ethylene and acetylene in the acetone solutions and to 1,1

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